Organic Synthesis - Organic Synthesis: Aromatic Compounds (A-Level Chemistry)
Organic Synthesis: Aromatic Compounds
Synthesis of Aromatic Compounds
A-Level Chemistry exam boards requires you to know the synthesis of different organic compounds. The flow diagram below summarises the synthesis of each functional group in aromatic compounds.
Worked Example: Name the mechanisms and reaction conditions for each of the steps 1,2,3 and 4
Answer:
Step 1: Nucleophilic addition elimination reaction with ethanoyl chloride at room temperature and pressure.
Step 2: Electrophilic substitution reaction with concentrated sulfuric acid and concentrated nitric acid producing the NO2+ electrophile.
Step 3: Hydrolysis of amide to make an amine.
Step 4: Reduction of nitro group to amine using tin and concentrated hydrochloric acid.
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