Transport in Cells - Factors that Affect the Rate of Diffusion (GCSE Biology)

Factors that Affect the Rate of Diffusion:

  • Difference in concentration affects the rate of diffusion. The greater the concentration gradient, the quicker diffusion takes place. For example, if there is a very high concentration of oxygen in the alveoli, and a very low concentration in the blood, diffusion will take place very quickly. However, if there is an almost equal concentration in both, the rate of diffusion will be very low.
  • The temperature affects the rate of diffusion. As the temperature increases, particles gain more kinetic energy and so can diffuse across a membrane more quickly. Therefore, as the temperature increases, the rate of diffusion increases.
  • The surface area of the membrane affects the rate of diffusion. As the surface area of the membrane increases, the rate of diffusion also increases, as there is more space for molecules to diffuse across the membrane.
  • Distance. The shorter the distance the substances have to move, the faster the rate of diffusion.
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FIck’s Law

Fick’s law basically describes the relationship between the different factors that affect the rate of diffusion:

Factors that Affect the Rate of Diffusion
Factors that Affect the
Rate of Diffusion

The ‘∝’ sign means ‘proportional to’, so if the factors in the numerator increase, the Rate of Diffusion will increase
proportionally. If the factor on the denominator decreases, then the rate of Diffusion will increase proportionally

For example, if the Rate of Diffusion doubles, then the Surface Area or Concentration also doubles OR the Membrane Thickness will half.

→What is diffusion in cells?

Diffusion is the movement of particles from an area of high concentration to an area of low concentration. In cells, diffusion is an important process for the transport of molecules and ions across the cell membrane.

→What factors affect the rate of diffusion in cells?

The rate of diffusion in cells is affected by factors such as temperature, concentration gradient, size of the molecule, and the presence of a membrane.

→How does temperature affect the rate of diffusion in cells?

An increase in temperature increases the energy of the particles, causing them to move more rapidly and increasing the rate of diffusion. On the other hand, a decrease in temperature reduces the energy of the particles and slows down the rate of diffusion.

→How does the concentration gradient affect the rate of diffusion in cells?

The concentration gradient is the difference in concentration of a substance between two areas. The greater the concentration gradient, the faster the rate of diffusion.

→How does the size of the molecule affect the rate of diffusion in cells?

Larger molecules move more slowly than smaller molecules due to their greater size and weight. As a result, larger molecules diffuse more slowly than smaller molecules.

→How does the presence of a membrane affect the rate of diffusion in cells?

The cell membrane acts as a barrier to diffusion, controlling the movement of molecules and ions in and out of the cell. The presence of the membrane can affect the rate of diffusion, depending on the permeability of the membrane to the specific molecule.

→Can changes in the rate of diffusion in cells have an impact on cell function?

Yes, changes in the rate of diffusion can have a significant impact on cell function. The transport of molecules and ions is important for maintaining the balance of substances within the cell, and changes in the rate of diffusion can disrupt these processes and result in changes in cell function.

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