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  • 200+ Video Tutorials for all parts of the specification
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A-Level Biology Course (£19/month - Monthly Subscription)

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A quick intro...

A-Level Biology is HARD, there’s no denying it! Trying to cram all the theory, memorising all the practicals and applying it all to exam techniques – don’t make it easy.

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200+ Video Tutorials

We have over 200 video tutorials covering each topic from every exam board specification

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Weekly Classes

We offer Biology weekly classes led by our expert Biology tutor as well as access to past recordings

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5000+ Flashcards

Pre-written flashcards for every topic so you can utilise the scientifically back active recall and spaced repetition studying techniques

We cover every A-Level Biology Specification

1. Biological Molecules
1 Lesson
35
60 Minutes

All living things are made up of three main types of biological molecules. By understanding more about these important molecules we can learn about how living organisms function at a molecular level.

Tutorials
Lesson 1Monomers and Polymers

The variety of life, both past and present, is extensive, but the biochemical basis of life is similar for all living things. Monomers are the smaller units from which larger molecules are made.

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Lesson 2Carbohydrates

Monosaccharides are the monomers from which larger carbohydrates are made. Polysaccharides are formed by the condensation of many monomer units.

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Lesson 3Lipids

Triglycerides and phospholipids are two groups of lipid.Triglycerides are formed by the condensation of one molecule of glycerol and three molecules of fatty acid.

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Lesson 4Proteins

Amino acids are the monomers from which proteins are made. A condensation reaction between two amino acids forms a peptide bond. A functional protein may contain one or more polypeptides.

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Lesson 5DNA and RNA

Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are important information-carrying molecules. In all living cells, DNA holds genetic information and RNA transfers genetic information from DNA to the ribosomes.

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Lesson 6ATP

A single molecule of adenosine triphosphate (ATP) is a nucleotide derivative and is formed from a molecule of ribose, a molecule of adenine and three phosphate groups.

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Lesson 7Water

Water is a major component of cells. It has several properties that are important in biology.

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Lesson 8Inorganic ions

Inorganic ions occur in solution in the cytoplasm and body fluids of organisms, some in high concentrations and others in very low concentrations.

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Lesson 9Nucleic Acids

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Lesson 10Practice Questions + Mark Schemes

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2. Cells
1 Lesson

All life on Earth exists as cells. These have basic features in common and differences between cells are due to the addition of extra features.

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Lesson 1Structure of Eukaryotic Cells

In complex multicellular organisms, eukaryotic cells become specialised for specific functions. Specialised cells are organised into tissues, tissues into organs and organs into systems.

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Lesson 2Cell Organelles

The structure of eukaryotic cells, restricted to the structure and function of intracellular organelles. These include the nucleus, ribosomes, chloroplasts, Golgi apparatus and others.

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Lesson 3Structure of Prokaryotes and Viruses

Viruses are acellular and non-living. The structure of virus particles includes genetic material, capsid and attachment protein.

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Lesson 4Cell Division and Cell Cycle

Within multicellular organisms, not all cells retain the ability to divide. Eukaryotic cells that do retain the ability to divide show a cell cycle.

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Lesson 5Binary Fission and Viral Replication

Being non-living, viruses do not undergo cell division. Following injection of their nucleic acid, the infected host cell replicates the virus particles.

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Lesson 6Investigating Mitosis

Set-up and use of an optical microscope to identify the stages of mitosis in these stained squashes and calculation of a mitotic index.

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Lesson 7Structure of Cell Membranes

The basic structure of all cell membranes, including cell-surface membranes and the membranes around the cell organelles of eukaryotes, is the same.

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Lesson 8Transport Across Cell Membranes

Cells may be adapted for rapid transport across their internal or external membranes by an increase in surface area of, or by an increase in the number of protein channels and carrier molecules in, their membranes.

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Lesson 9Binary Fission

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Lesson 10Practice Questions + Mark Schemes

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3. Immunity
1 Lesson

Each type of cell has specific molecules on its surface that identify it. These molecules include proteins and enable the immune system to identify pathogens, cells from other organisms of the same species, abnormal body cells and toxins.

Tutorials
Lesson 1Antigens

An antigen is any substance that when introduced into the blood or tissue induces the production of antibodies. Antigens are usually large complex molecules such as proteins or glycoproteins.

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Lesson 2Phagocytosis

Phagocytosis is a process wherein a cell binds to the item it wants to engulf on the cell surface and draws the item inward while engulfing around it.

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Lesson 3Adaptive Immunity

Adaptive immunity is immunity you develop over your lifetime. It can come from: a vaccine, exposure to an infection or disease

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Lesson 4Vaccinations

Vaccines are used to provide protection for individuals and populations against disease.

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Lesson 5HIV

Human immunodeficiency virus (HIV) replicated in helper T cells. After infection HIV causes the symptoms of AIDS.

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Lesson 6Antigens and Self Tolerance

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Lesson 7Antibodies

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Lesson 8Types of Immunity and Vaccination

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Lesson 9Immunity Tutorials

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Lesson 10Practice Questions + Mark Schemes

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4. Exchange
1 Lesson

The internal environment of a cell or organism is different from its external environment. The exchange of substances between the internal and external environments takes place at exchange surfaces. To truly enter or leave an organism, most substances must cross cell plasma membranes.

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Lesson 1Surface Area to Volume Ratio

Changes to body shape and the development of systems in larger organisms as adaptations that facilitate exchange as this ratio reduces.

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Lesson 2Gas Exchange

Ventilation and the exchange of gases occurs in the human lungs. The mechanism of breathing to include the role of the diaphragm and the antagonistic interaction between the external and internal intercostal muscles in bringing about pressure changes in the thoracic cavity.

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Lesson 3Digestion and Transport

During digestion, large biological molecules are hydrolysed to smaller molecules that can be absorbed across cell membranes.

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Lesson 4Mass Transport in Animals

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Lesson 5Lung Disease

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Lesson 6Correlation and Causation

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Lesson 7Pollution and Smoking

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Lesson 8Plants vs Animals

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Lesson 9Adaptation

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Lesson 10Practice Questions + Mark Schemes

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5. DNA and Genes
1 Lesson

Genetic diversity within a species can be caused by gene mutation, chromosome mutation or random factors associated with meiosis and fertilisation. This genetic diversity is acted upon by natural selection, resulting in species becoming better adapted to their environment.

Tutorials
Lesson 1DNA, Genes and Chromosomes

In the nucleus of eukaryotic cells, DNA molecules are very long, linear and associated with proteins, called histones. Together a DNA molecule and its associated proteins form a chromosome.

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Lesson 2Protein Synthesis

The genome is the complete set of genes in a cell and the proteome is the full range of proteins that a cell is able to produce. mRNA is used by the cell to produce proteins.

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Lesson 3Mutations

Gene mutations involve a change in the base sequence of chromosomes. They can arise spontaneously during DNA replication and include base deletion and base substitution.

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Lesson 4Evolution and Natural Selection

Genetic diversity is a factor enabling natural selection to occur. Natural selection results in species that are better adapted to their environment. These adaptations may be anatomical, physiological or behavioural.

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Lesson 5Species and Taxonomy

Two organisms belong to the same species if they are able to produce fertile offspring. A phylogenetic classification system attempts to arrange species into groups based on their evolutionary origins and relationships.

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Lesson 6Biodiversity

Biodiversity can relate to a range of habitats, from a small local habitat to the Earth. An index of diversity describes the relationship between the number of species in a community and the number of individuals in each species.

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Lesson 7Inheritance

Alleles may be dominant, recessive or codominant. In a diploid organism, the alleles at a specific locus may be either homozygous or heterozygous.

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Lesson 8Populations in Ecoystems

Individuals within a population of a species may show a wide range of variation in phenotype. This is due to genetic and environmental factors. The primary source of genetic variation is mutation.

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Lesson 9Biodiversity within a Community

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Lesson 10Meiosis

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Lesson 11Practice Questions + Mark Schemes

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6. Energy Transfers
1 Lesson

Life depends on continuous transfers of energy. In photosynthesis, light is absorbed by chlorophyll and this is linked to the production of ATP. In respiration, various substances are used as respiratory substrates. The hydrolysis of these respiratory substrates is linked to the production of ATP.

Tutorials
Lesson 1Photosynthesis

Photosynthesis is the name of the process whereby organisms convert light energy from the sun into sugar and other organic molecules. They can then go on to use these substances as chemical energy, in the same way, that humans use food. Photosynthesis is essential for almost all life on earth.

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Lesson 2Respiration

Respiration is a set of metabolic reactions and processes that take place within the cells of organisms. It stores biochemical energy within adenosine triphosphate (ATP) molecules. There are two types of respiration, aerobic and anaerobic. Respiration is the process of making ATP rather than breaking it down.

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Lesson 3Energy and Ecosystems

In any ecosystem, plants synthesise organic compounds from atmospheric, or aquatic, carbon dioxide. Most of the sugars synthesised by plants are used by the plant as respiratory substrates. The rest are used to make other groups of biological molecules. These biological molecules form the biomass of the plants.

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Lesson 4Nutrient Cycles

Nutrients are recycled within natural ecosystems, exemplified by the nitrogen cycle and the phosphorus cycle. Microorganisms play a vital role in recycling chemical elements such as phosphorus and nitrogen.

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Lesson 5Light Dependant Reactions

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Lesson 6Light Independent Reactions

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Lesson 7Krebs Cycle

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Lesson 8Link Reactions

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Lesson 9NPP and GPP

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Lesson 10Practice Questions + Mark Schemes

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7. Environment Responses
1 Lesson

A stimulus is a change in the internal or external environment. Living organisms need to be able to respond to these changes in order to survive.

Tutorials
Lesson 1Survival and Response

Organisms increase their chance of survival by responding to changes in their environment. Taxes and kineses as simple responses that can maintain a mobile organism in a favourable environment.

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Lesson 2Receptors

A receptor detects a stimulus. A coordinator formulates a suitable response to a stimulus. An effector produces a response. Receptors are specific to one type of stimulus.

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Lesson 3Heart Rate

Cardiac muscle is myogenic, meaning it can contract and relax without receiving signals from the nervous system. Receptors pick up changes in the blood and transfer this to sensory nerves to alter heart rate.

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Lesson 4Nerve Impulses

Changes in membrane permeability lead to depolarisation and the generation of an action potential in nerve cells.

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Lesson 5Synaptic Transmission

The junction where two neurones meet is known as a synapse. A synapse consists of a presynaptic knob, synaptic cleft and postsynaptic membrane ·

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Lesson 6Skeletal Muscle Effectors

Skeletal muscles are stimulated to contract by nerves and act as effectors. Muscles act in antagonistic pairs against an incompressible skeleton.

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Lesson 7Homeostasis and Negative Feedback

Homeostasis is the maintenance of a stable internal environment. Homeostasis in mammals involves physiological control systems that maintain the internal environment within restricted limits.

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Lesson 8Blood Glucose Control

Insulin is a hormone released from β-cells in the pancreas when blood glucose concentration rises in order to lower the concentration back to its optimum via negative feedback.

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Lesson 9Control of Blood Water Potential

The kidneys are made if nephrons which help filter the blood. The blood undergoes ultrafiltration at the glomerulus due to the smaller diameter of the efferent arteriole than the afferent arteriole, creating high hydrostatic pressure.

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Lesson 10Practice Questions + Mark Schemes

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8. Gene Expression
1 Lesson

Cells are able to control their metabolic activities by regulating the transcription and translation of their genome. Although the cells within an organism carry the same coded genetic information, they translate only part of it. In multicellular organisms, this control of translation enables cells to have specialised functions, forming tissues and organs.

Tutorials
Lesson 1Using Genome Projects

Determining the genome of simpler organisms allows the sequences of the proteins that derive from the genetic code (the proteome) of the organism to be determined. This may have many applications, including the identification of potential antigens for use in vaccine production.

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Lesson 2Alteration of Base Sequences

Gene mutations might arise during DNA replication. They include addition, deletion, substitution, inversion, duplication and translocation of bases.

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Lesson 3Control of Transcription and Translation

In eukaryotes, transcription of target genes can be stimulated or inhibited when specific transcriptional factors move from the cytoplasm into the nucleus. The role of the steroid hormone, oestrogen, in initiating transcription.

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Lesson 4Gene Expression

There are many factors that control the expression of genes and, thus, the phenotype of organisms. Some are external, environmental factors, others are internal factors. The expression of genes is not as simple as once thought, with epigenetic regulation of transcription being increasingly recognised as important.

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Lesson 5DNA Probes

The use of labelled DNA probes that can be used to screen patients for heritable conditions, drug responses or health risks.

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Lesson 6Genetic Fingerprinting

The technique of genetic fingerprinting in analysing DNA fragments that have been cloned by PCR, and its use in determining genetic relationships and in determining the genetic variability within a population.

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Lesson 7Recombinant DNA

Recombinant DNA technology involves the transfer of fragments of DNA from one organism, or species, to another. Since the genetic code is universal, as are transcription and translation mechanisms, the transferred DNA can be translated within cells of the recipient (transgenic) organism.

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Lesson 8Dominant VS Recessive

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Lesson 9Monohybrid and Dihybrid Inheritance

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Lesson 10Sex VS Autosomal Linkage

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Lesson 11Epistasis

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Lesson 12Chi-Squared Test

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Lesson 13Practice Questions

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Want to achieve the highest possible A-Level results? If this is the case, we strongly suggest you take part in our weekly A-Level Biology classes. We break down your thought process and aim to enhance and polish your exam technique over time in our A-level Biology courses.

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A-Level Biology Course (£19/month - Monthly Subscription)

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A-Level Biology Course (£19/month - Monthly Subscription)

The A-Level course is a monthly subscription.

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Drill yourself till you’re 100% prepared for the big day

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A-Level Biology Course (£19/month - Monthly Subscription)

The A-Level course is a monthly subscription.

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